The Italian G20 Presidency comes at a critical time in the history of the G20. Collective action across the G20 and beyond is required to promote recovery from the Covid-19 pandemic, both in terms of global health and economic prosperity. Furthermore, this recovery needs to be environmentally sustainable and socially inclusive. Never before has the agenda of the G20 been both so urgent and so wide, extending over the economic, health, environmental and social domains. How are the priorities of the Italian G20 Presidency - encapsulated in “People, Planet, Prosperity” - to be achieved? How can resilience in health systems be achieved while avoiding protectionism and vaccine nationalism? How can international efforts to secure a global equitable distribution of vaccines and medical equipment be promoted? How can duplication in these efforts be avoided? How can the economic recovery be coordinated to ensure adaptation to a “new normal” that is greener, more digital and human-centric than the previous status quo? How does digital governance need to be reformed in order to achieve these ends? This panel will discuss these and other pressing problems of global collective action, setting the stage for a fruitful exchange between policymakers, business leaders, researchers, and civil society.